Aspartic Acid can be found naturally in plant proteins, is a non essential amino acid that may be interconvertible with the amino acid Asparagine. Asparatic acid is synthesized from the amino acid glutamate.
Aspartic acid is converted intracellularly into oxaloacetate, a substrate in the energy-producing Krebs cycle, and is a carrier molecule for the transport of potassium and magnesium into the cell. L-Aspartic Acid is central to the formation of both RNA and DNA the pancreatic cells and insulin production of aspartic acid are in position 57 of the DNA chain. Aspartic acid is alanine with one of the β hydrogens replaced by a carboxylic acid group.
Aspartic acid can help some body functions such as metabolism during the process of constructing amino acids and biochemicals, as well as generating immunoglobulin and antibodies. Aspartic acid is beneficial for neural health, assists the liver to remove excess toxins and waste from the circulatory system by ridding itself of highly toxic ammonia.
Aspartic Acid may be interconvertible with the amino acid Asparagine. Asparatic acid is synthesized from glutamate. Aspartic Acid aids in the expulsion of harmful ammonia from the body. Ammonia in the circulatory system is a highly toxic substance, which is also harmful to the central nervous system.
Aspartic Acid is interconvertible with Asparagine and have many common functions including:
Helps protect the liver by aiding the removal of ammonia.
Involved in DNA and RNA metabolism
Involved in immune system function by enhancing immunoglobulin production and anti-body formation
One of the two main “excitatory” amino acids groups, the other being Glutamate (Glutamic Acid)
Asparatic acid is a natural dibasic amino acid, involved in transamination reactions, the ornithine cycle, and the formation of carnosine, anserine, purines, and pyrimidines.
1. Has a protective function over the liver.
2. Helps in detoxification of ammonia.
3. Promotes mineral uptake in the intestinal tract.
Increases resistance to fatigue
Involved in the formation of RNA and DNA, the chemical bases of heredity and carriers of genetic information
Salts of aspartic acid increase stamina and endurance
Protects the liver and promotes normal cell function
Builds up the immune system, producing immunoglobulins and antibodies
Recent studies have shown that Aspartic Acid may increase resistance to fatigue and increase endurance.
Aspartic Acid assists in detoxification of ammonia and as a result provides protection to the liver. Aspartic Acid promotes uptake of other toxins from the bloodstream and trace elements in the gut. Aspartic Acid also connects the nitrogen and carbohydrate metabolism which is responsible for a large part of the energy cycle in the body. Aspartic Acid assists in the transport of magnesium and potassium to cells.
First isolated in 1868 from legumin in plant seed.
Aspartic Acid is used as dietetic supplement, additive for kinds of soft drink. In medicine, it is used as ammoniac detoxicating agent. hepar function accelerator and fatigue refresher. Aspartic acid is one of two acidic amino acids. Aspartic acid and glutamic acid play important roles as general acids in enzyme active centers, as well as in maintaining the solubility and ionic character of proteins. Proteins in the serum are critical to maintaining the pH balance in the body; it is largely the charged amino acids that are involved in the buffering properties of proteins. Aspartic acid is alanine with one of the β hydrogens replaced by a carboxylic acid group. The pKa of the β carboxyl group of aspartic acid in a polypeptide is about 4.0. Note that aspartic acid has an α-keto homolog, oxaloacetate, just as pyruvate is the α-keto homolog of alanine. Aspartic acid and oxaloacetate are interconvertable by a simple transamination reaction, just as alanine and pyruvate are interconvertible.
Aspartic Acid is one of two amino acids (the other is glutamic acid) that has a negatively charged carboxylate group on the side chain. This gives Aspartic Acid an overall negative charge at physiological hydrogen ion concentrations (approximately pH 7.3). Although Aspartic Acid is considered a non-essential amino acid, it plays a paramount role in metabolism during construction of other amino acids and biochemicals in the citric acid cycle. Among the biochemicals that are synthesized from Aspartic Acid are asparagine, arginine, lysine, methionine, threonine, isoleucine, and several nucleotides.
Aspartic Acid is found in abundance in plant proteins, especially in sprouting seeds but can be manufactured in the body from oxaloacetic acid. Found in dairy, beef, poultry, sprouting seeds
Aspartic Acid is synergistic with Vitamin B6, zinc, magnesium and potassium.
Deficiency Signs or Symptoms:
Calcium and magnesium deficiencies. Because of this, low aspartic acid levels should lead the health care professional to test for calcium and/or magnesium deficiencies.
Amyotrophic Lateral Sclerosis (ALS or Lou Gehrig's Disease), Epilepsy, especially right after a seizure, Stroke
†The statements on this Web site have not been evaluated by the Food and Drug Administration (FDA). And are not intended to diagnose, treat, cure or prevent disease. The information presented is not intended to replace medical advice or treatment from your own doctor or healthcare provider. Nothing presented here is intended as a substitute for prescription medication or any other medical treatment prescribed by your doctor.