Phenylalanine is an electrically-neutral, nonpolar essential amino acid. Phenylalanine is one of the twenty common amino acids used to biochemically form proteins, coded for by DNA.
Phenylalanine is structurally closely related to dopamine, epinephrine (adrenaline) and tyrosine. Phenylalanine is a direct precursor to the neuromodulator phenylethylamine.
The biosynthesis of other amino acids and some neurotransmitters are derived from Phenylalanine. Phenylalanine can be converted to tyrosine by a biochemical process in the liver.
Phenylalanine in the L-form s required by the thyroid for normal function, controls appetite, and act as an anti-depressant by increasing moods. May enhance the ability to learn and the retention of memory.
L-Phenylalanine produces neurotransmitters that the brain uses to manufacture norepinephrine, a natural stimulant that creates a sense of well being. Phenylalanine is involved in the production of phenylethylamine, a brain stimulant. L-Phenylalanine inhibits enzymes that break down endorphin hormones.
L-phenylalanine has been shown to be involved in the control of appetite. Phenylalanine has been demonstrated that in the gut, phenylalanine, triggers the release of cholecystokinin (CCK). CCK may induce satiety. Phenylalanine is being used today as an appetite suppressant. Phenylalanine is a precursor to norepinephrine (the brains version of adrenaline) and dopamine in the brain.
Precursor to Tyrosine, which, in turn, is the precursor to the neurotransmitters: Dopamine and the excitatory neurotransmitters Norepinephrine and Epinephrine.
Precursor to the hormone, Thyroxine.
Enhances mood, clarity of thought, concentration, and memory.
Major part of collagen formation.
While the L-form of all of the other amino acids is the one that is beneficial to people, the D and DL forms of Phenylalanine have been useful in treating pain.
DL-Phenylalanine is useful in reducing arthritic pain.
Used in the treatment of Parkinson's Disease.
See Tyrosine. It is more powerful and safe in raising the level of norepinephrine, and thereby treating depression.
Phenylalanine is the most commonly found aromatic amino acid in proteins and enzymes with a molar ratio of 3.5 percent compared to the other amino acids, about double the amount of any other aromatic amino acid.
Studies have shown that depressed people seem to have extremely low levels of phenylethylamine.
Clinical research found that when endorphins were administered intravenously sudden and dramatic anti-depressant actions occurred, especially in suicidal patients. L-Phenylalanine inhibits enzymes that break down endorphin hormones.
Caution: Phenylalanine should be avoided in:
High blood pressure. Has hypertensive properties and should be avoided with people with high blood pressure.
Panic disorder/anxiety attacks.
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