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“Isomerases”  [EC 5] 

Isomerase Reactions

  In enzyme science, Isomerase Reactions are a group of broad Top-level Enzyme Reactions (Enzyme Catalysts), involved with intramolecule rearrangement of isomers, in the Top-level Enzyme Reaction Group EC 5.

Isomerases

  In biochemistry, an In enzyme science, Isomerase Reactions are a class of enzymes that catalyze geometric or structural rearrangement of isomers within the molecule to form a single product, not involving a net change in the concentrations of compounds other than the substrate and the product.
  Examples of some isomerase enzyme reactions include:

• epimerases and racemases [EC 5.1]
  • Amino Acid Isomerases [EC 5.1.1]
  • Epimerases & Racemases acting on Hydroxy Acids & Derivatives [EC 5.1.2]
  • Carbohydrate Epimerases [EC 5.1.3]
  • Epimerases & Racemases acting on other Compounds [EC 5.1.99]
• cis-trans-isomerases [EC 5.2]
  • peptidylprolyl isomerase [EC 5.2.1.8]
    • Immunophilins
      • Cyclophilins
        • Cyclophilin A
        • Cyclophilin C
      • Tacrolimus Binding Proteins
        • Tacrolimus Binding Protein 1A
    • NIMA-Interacting Peptidylprolyl Isomerase
    • Peptidyl-Prolyl Cis-Trans Isomerase NIMA-Interacting 4
• intramolecular oxidoreductases [EC 5.3]
  • Aldose-Ketose Isomerases +
  • Carbon-Carbon Double Bond Isomerases +
  • Prostaglandin-E Synthases
  • Sulfur-Sulfur Bond Isomerases +
  • Thromboxane-A Synthase
• intramolecular transferase enzymes [EC 5.4]
  • Transferring acyl groups [EC 5.4.1]
  • Phosphotransferases (phosphomutases) [EC 5.4.2]
    • Bisphosphoglycerate Mutase
    • Phosphoglucomutase
    • Phosphoglycerate Mutase
  • Transferring amino groups [EC 5.4.3]
  • Transferring hydroxy groups [EC 5.4.4]
  • Transferring other groups [EC 5.4.99]
    • 2-Acetolactate Mutase
    • Chorismate Mutase
      • Prephenate Dehydratase
      • Prephenate Dehydrogenase
    • Methylmalonyl-CoA Mutase
• DNA topoisomerases
  • DNA topoisomerase type I
  • DNA topoisomerase type II
    • DNA gyrase
    • DNA topoisomerase type IV
• Intramolecular Lyases
  • Myo-Inositol-1-Phosphate Synthase
• DNA helicase (DNA unwinding proteins)
  • DnaB Helicases
  • Ku Autoantigen
  • Minichromosome Maintenance Proteins +
  • RecQ Helicases +
  • Xeroderma Pigmentosum Group D Protein

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