“Myokines”  

  Myokines are a type of cytokines that play a role as a soluble mediator of the immune response, neither as an antibodies nor a complement.
  Myokine proteins are produced largely, but not exclusively, by monocytes and macrophages.
  Examples of myokines include:

• myostatin (GDF-8)
• irisin
• Interleukin 15 (IL-15)
• Brain-derived neurotrophic factor (BDNF)
• decorin (bone proteoglycan II)
• Osteonectin (SPARC)

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