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Biology |26069|
See Also ↔
 
 
“Systems Biology”  
  Systems Biology is a Bioscience (Biology) branch that focuses on complex interactions in biological systems, using a holism perspective.
  Systems Biology includes the study of the interactions between the components of our biological systems, and how these interactions give rise to the function and behavior of that system. *
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“Metabolomic Science (Metabolomics)”  

Metabolomics

  The science of Metabolomics (Metabolomic Science) is an associated discipline of the Systems Biology in the study of chemical processes involving metabolites that also includes: Organismal, tissue, or cell level measurements of all these small-molecules. **
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“Glycomics”  
  The science of Glycomics is a subset of glycobiology and an associated discipline of the systems biology in the study of all organismal glycan structures and cell level measurements of carbohydrates (glycomes) including genetic, physiologic, pathologic, and other aspects. **
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“Genomics”  
  The science of Genomics is an associated discipline of the Systems Biology that includes the: Organismal deoxyribonucleic acid (DNA) sequence, including intra-organisamal cell specific variation. (i.e. Telomere length variation etc.).
  Examples of genomic topics and concepts include:
  • Epigenomics
  • Glycomics
  • HapMap Project
  • Human Genome Project
  • Nutrigenomics
  • Proteomics
    • Proteogenomics
**
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“Epigenomics (Epigenetics)”  

Epigenomics

  Epigenomics is the study of the complete set of epigenetic modifications on the genetic material of a cell, known as the epigenome
  The science of Epigenomics (Epigenetics) is an associated discipline of the Systems Biology that includes the: Organismal and corresponding cell specific transcriptomic regulating factors not empirically coded in the genomic sequence. (i.e. DNA Methylation, Histone Acetelation etc). **
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“Lipidomics”  
  The science of Lipidomics is an associated discipline of the Systems Biology in the study of: Organismal, tissue, or cell level measurements of lipids and the pathways and networks of cellular lipids in biological systems. **
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“Proteomics”  
  The science of Proteomics (Translatomics), as an associated discipline of the systems biology, is the study of the proteomes including the study of: organismal, tissue, or cell level measurements of proteins and peptides via two-dimensional gel electrophoresis, mass spectrometry or multi-dimensional protein identification techniques (advanced HPLC systems coupled with mass spectrometry).
  Sub disciplines of Proteomics (Translatomics) include phosphoproteomics, glycoproteomics and other methods to detect chemically modified proteins. **
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References & Citations:
1. Freeze HH. et al "Neurology of inherited glycosylation disorders"   Lancet Neurol. 2012 May;11(5):453-66  
2. Sorrenti V. et al "Deciphering the Role of Polyphenols in Sports Performance: From Nutritional Genomics to the Gut Microbiota toward Phytonutritional Epigenomics"   Nutrients. 2020 Apr 29;12(5):1265  
3. Wenk MR. "The emerging field of lipidomics"   Nat Rev Drug Discov. 2005 Sep;4(9):725  
4. Graves PR. et al "Molecular biologist's guide to proteomics"   Microbiol Mol Biol Rev. 2002 Mar;66(1):39-63; table of contents  
 
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