“Multienzyme Complexes”  

Multienzyme Complex

  In our body, Multienzyme Complexes, as a type of multiprotein complex, with systems of enzymes which function sequentially by catalyzing consecutive reactions linked by common metabolic intermediates.
  Examples of multienzyme complexes include:

• anthranilate phosphoribosyltransferase enzyme complex
• electron transport chain enzyme complex
• exosome multienzyme ribonuclease complex (exosome complex)
• Fatty Acid Synthase, Type II (enzyme complex)
• glycine decarboxylase enzyme complex
• ketoglutarate dehydrogenase enzyme complex
• Mi-2 nucleosome remodeling and deacetylase enzyme complex
• phosphoenolpyruvate sugar phosphotransferase enzyme system
• photosynthetic reaction center enzyme complex
• polyketide synthase enzyme complexesprostaglandin-endoperoxide synthase enzyme complex
• proteasome endopeptidase complex
• pyruvate dehydrogenase enzyme complex
• Sin3 histone deacetylase and corepressor complex
• STAGA complex
• sucrase-isomaltase complex
• Tryptophan Synthase (enzyme complex)
• Viral Replicase Complex Proteins

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  Examples of multienzyme complexes include:

• Acetyl-CoA Carboxylase
• N-Acetyllactosamine Synthase
• aspartate carbamoyltransferases
• Aspartokinase Homoserine Dehydrogenase
• Cyclin-Dependent Kinase 9
• Dual-Specificity Phosphatases
  • cdc25 Phosphatases
  • Dual Specificity Phosphatase 1
  • Dual Specificity Phosphatase 2
  • Dual Specificity Phosphatase 3
  • Dual Specificity Phosphatase 6
• fatty acid synthases
  • fatty acid synthase type I
  • fatty acid synthase type II
• Lactase-Phlorizin Hydrolase
• Mitochondrial Trifunctional Protein
  • Mitochondrial Trifunctional Protein alpha Subunit
  • Mitochondrial Trifunctional Protein beta Subunit
• Peroxiredoxin VI
• Peroxisomal Bifunctional Enzyme
• Peroxisomal Multifunctional Protein-2
• Phosphofructokinase-2

Also:

• Electron Transport Complex I
• Electron Transport Complex IV
• Glycine Decarboxylase Complex
• ketoglutarate dehydrogenase enzyme complex
• Phosphoenolpyruvate Sugar Phosphotransferase System
• photosynthetic reaction proteins
  • Photosystem I Protein Complex
  • Photosystem II Protein Complex
  • Cytochrome b6f Complex +
  • light-harvesting protein complexes +
• Proteasome Endopeptidase Complex
• Pyruvate Dehydrogenase Complex
• Succinate Cytochrome c Oxidoreductase
• Sucrase-Isomaltase Complex

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“Pyruvate Dehydrogenase Complex”  

  In enzyme science, the Pyruvate Dehydrogenase Complex is the multienzyme complex responsible for the formation of acetyl coenzyme A from pyruvate.

In our body, pyruvate dehydrogenase complex catalyzes the oxidative decarboxylation of pyruvate to produce acetyl-CoA and NADH, and is the gate-keeper enzyme that strategically links glycolysis to the Krebs cycle and lipogenic pathways.
  The pyruvate dehydrogenase enzyme complex, converts pyruvate into acetyl-CoA by the pyruvate decarboxylation process, and is composed of multiple copies of three enzymatic components:

• pyruvate dehydrogenase (acetyl-transferring) (E1)
  • pyruvate dehydrogenase E1 alpha 1 subunit
  • pyruvate dehydrogenase E1 beta subunit
• dihydrolipoamide S-acetyltransferase (E2)
• lipoamide dehydrogenase (E3) aka pyruvate dehydrogenase (lipoamide)

  The genes of the pyruvate dehydrogenase enzyme complex gene family include:

• E1
  • PDHA1 gene encoding the pyruvate dehydrogenase E1 alpha 1 subunit
  • PDHB gene encoding the pyruvate dehydrogenase E1 beta subunit
• DLAT gene encoding the dihydrolipoamide S-acetyltransferase (E2)
• DLD gene encoding the dihydrolipoamide dehydrogenase (E3)
• PDHX gene encoding the pyruvate dehydrogenase complex component X

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“Glycine Decarboxylase Complex (Glycine Cleavage System Complex)”  

Glycine Decarboxylase Complex

  In our body, Glycine Decarboxylase Complex (Glycine Cleavage System Complex) is an amino acid oxidoreductase multienzyme complex, that catalyzes the oxidative decarboxylation and deamination of glycine into carbon dioxide, ammonia, NADH, and N5N10-methylenetetrahydrofolate, composed of four different component protein components referred to as H, P, L, and T. **

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“Proteasome Endopeptidase Complexes (Proteasome Complexes”  

Proteasome Complexes

  In our body's cells, Proteasome Endopeptidase Complex (Proteasome Complex) performs regulated ubiquitin-dependent cytosolic and nuclear proteolysis, in the nucleus and the cytoplasm.
  In biochemistry, the peptide hydrolase, proteasome endopeptidase complex, is a multienzyme complexes, with a hydrolase enzyme reaction.
  The proteasome complex subunits include:

PSMA1 gene PSMA2 gene PSMA3 gene PSMA4 gene PSMA5 gene PSMA6 gene PSMA7 gene PSMA8 gene PSMB1 gene PSMB2 gene PSMB3 gene

PSMB4 gene PSMB5 gene PSMB6 gene PSMB7 gene PSMB8 gene PSMB9 gene PSMB10 gene PSMC1 gene PSMC2 gene PSMC3 gene PSMC4 gene

PSMC5 gene PSMC6 gene PSMD1 gene PSMD2 gene PSMD3 gene PSMD4 gene PSMD5 gene PSMD6 gene PSMD7 gene PSMD8 gene PSMD9 gene

PSMD10 gene PSMD11 gene PSMD12 gene PSMD13 gene PSMD14 gene SEM1 gene (PSMD15 gene) ADRM1 gene (PSMD16 gene) PSME1 gene PSME2 gene PSME3 gene PSME4 gene PSMF1 gene

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“Photosynthetic Reaction Center Complex Proteins”  

Photosynthetic Reaction Proteins

  In protein science, Photosynthetic Reaction Proteins are protein complexes that take part in the process of photosynthesis, located as thylakoid membrane proteins within the thylakoids membranes of plant chloroplasts and a variety of structures in more primitive organisms.
  Examples of photosynthetic reaction proteins include:

• Photosystem I Protein Complex
• Photosystem II Protein Complex
• cytochrome b6f complex
  • Cytochromes b6
  • cytochromes f
  • plastoquinol-plastocyanin reductase
• light-harvesting protein complexes
  • Chlorophyll Binding Proteins
  • Phycobilisomes   +

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